Bolognia - Dermatology - 2nd Edition  (CHM Version)

    SOURCE :
        Bolognia - Dermatology - 2nd Edition

    AUTHORS :
        Jean L Bolognia, MD
            Professor of Dermatology, Department of Dermatology, Yale Medical School, New Haven, CT, USA
        Joseph L Jorizzo, MD
            Professor and Former (Founding) Chair, Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC, USA
        Ronald P Rapini, MD
            Professor and Chair, Department of Dermatology, University of Texas Medical School, and MD Anderson Cancer Center, Houston, TX, USA

    SUMMARY :
        The practice of dermatology is based upon a visual approach to clinical disease, with the development of an appreciation of recurrent patterns and images. The entire spectrum of our discipline, from the generation of clinicopathologic differential diagnoses to the orientation of rotational flaps, relies upon imagery. As a result, visualization also plays a critical role in how we integrate new information into pre-existing frameworks that serve as the hard drives of our medical memory.
        In the textbook Dermatology there is a strong emphasis on visual learning. This commitment is reflected in the use of schematic diagrams to convey the principles of skin biology as well as cutaneous surgery, and the inclusion of algorithms, which provide a logical as well as practical approach to commonly encountered clinical problems. The majority of the basic science is integrated throughout the book and appears as introductory chapters to the various sections. All illustrations and graphics are in color and photomicrographs demonstrating key histologic findings are found interspersed within the clinical chapters. These chapters also contain tables that attempt to provide weighted differential diagnoses and a ‘ladder’ approach to therapeutic interventions. Lastly, color-coding of sections allows easy and rapid access to required information.
        The ultimate goal of Dermatology is for it to never make its way to the bookshelf because it is being used on a weekly, or perhaps even daily, basis. Hopefully, this book will function as a colleague, albeit a non-verbal one, who is easily approachable and possesses the necessary expertise to provide succinct, up-to-date information that is both precise and practical. Realizing this goal required the time and energy of our contributors who have unselfishly shared their knowledge and experience with literally thousands of patients from around the world, and we thank them.
   

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Medical Microbiology - The Instant Notes Series(PDF Version)

    SOURCE :
        Medical Microbiology - The Instant Notes Series

    AUTHORS :
        William Irving
        Tim Boswell
        Del Ala’Aldeen

    SUMMARY :
        Medical microbiology is potentially an intimidating subject for new students. Not only does it appear to have a language all of its own, including plenty of obscure Latin terminology, but it covers a bewilderingly wide range of material, from the molecular biology of the infectious agents themselves (of which there is an alarmingly large—and ever-increasing—number) right through to the clinical management of the infected patient, passing disease pathogenesis, diagnosis, and the use of antimicrobial therapy on the way. This book seeks to identify, explain and expound upon the essentials of each of these aspects of the subject, in suitable ‘bite-sized’ chunks (a philosophy inherent in all of the books in the Instant Notes series).
        We do not expect students to start this book at page 1 and work their way meticulously through to the last page (although to do so would undoubtedly assist them in gaining excellent examination marks!). Many courses concerned with medical microbiology will have their own particular emphasis, and will provide scant, if any, cover of the other aspects of the subject. Also, certainly at undergraduate level, it is unlikely that any one course would intend to cover each and every microbe, at least not in the same depth of detail. It would be appropriate therefore for students undertaking those courses to concentrate on the subject areas and microorganisms relevant to their own course. Nevertheless, as practising medical microbiologists, we felt it entirely appropriate to aim to cover the many facets of our subject in a single text, and also to be comprehensive in dealing with all of the infectious agents with which our patients present on a routine basis.
        The book is divided into a number of sections. In section A we provide introductory background information on the nature of the infectious agents, the host response to infection, and how micro- organisms give rise to disease. Sections B, C, and D deal with the organisms themselves in more detail, the sections being ordered from the least (viruses) to the most (eukaryotes) structurally complicated. Within these sections, each group of related organisms is dealt with in a separate topic, which are ordered, very roughly, according to their clinical importance, and, for the bacteria, their Gram stain characteristics. Section E is concerned with general principles of the laboratory diagnosis and management of infection, including the mechanisms of action of antimicrobial agents, and possible strategies for prevention of infection. The final section, F, deals with infection from the point of view of the patient, i.e. clinical microbiology.

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Mayo Clinic - Internal Medicine REVIEW - 8th Edition(PDF Version)

    SOURCE :
        Mayo Clinic - Internal Medicine - 8th Edition

    AUTHORS :
        Amit K. Ghosh, MD

    SUMMARY :
        Medical advances have been occurring at breathtaking speed, with diagnostic and treatment options becoming available for conditions for which none previously existed. However, several aspects of health care remain the same. Patients continue to rely heavily on clinicians for help in understanding the burgeoning evidence in medical research and for providing optimal health care. Clinicians remain steadfast in their quest to meet the needs of their patients and to encourage innovation in meeting those needs. The focus on patient safety and quality of care remains a key- stone of medical practice, and multidisciplinary care with a system-based approach is increas- ingly being adopted to manage chronic disorders. The associated demands and challenges mandate that physicians remain abreast of the latest developments in medicine. To assist physicians in this endeavor, the Department of Internal Medicine at Mayo Clinic provides continuing medical education updates and resources in a timely manner. This book, Mayo Clinic Internal Medicine Review, is designed to meet the needs of practicing clinicians and physicians-in-training by updating their knowledge of internal medicine and helping to prepare them for the internal medicine cer- tification and maintenance of certification examinations administered by the American Board of Internal Medicine (ABIM).
        The success of the earlier editions of this textbook is exemplified by the number of books pub- lished. The positive reaction to and the success enjoyed by the earlier editions prompted the Department of Internal Medicine to proceed with the publication of the eighth edition. Each chapter has been thoroughly updated, and a new chapter on hospital medicine has been added. The goal is to provide an update in internal medicine that is readable and easy to study.
        This book is divided into chapters based on subspecialty topics and written by authors with expertise in the respective fields of medicine. Bulleted items highlight elements that are impor- tant concepts. The repetition of important points in the chapters reinforces the essential aspects of the topics and serves as an additional aid in review of the subjects. Multiple-choice ques- tions appear at the end of each chapter; there are more than 350 multiple-choice questions in this edition. Correct answers and detailed explanations follow the questions.
        I am grateful to all the individuals who contributed ideas and suggestions for improvement during the development of this book. I thank the esteemed authors of the previous editions for their input into this edition and for permitting the use of some of the materials from previous editions. I am indebted to all authors for their immense effort and contributions to this edi- tion. I thank the staffs of the Section of Scientific Publications, Department of Medicine, and Division of Media Support Services at Mayo Clinic for their contributions to this edition. The support and cooperation of the publisher, Informa Healthcare, are also gratefully acknowledged.
        I trust that the eighth edition of Mayo Clinic Internal Medicine Review will continue to update and advance the reader’s knowledge of internal medicine.
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Braunwald's Heart Disease - A Textbook Of Cardiovascular Medicine - 9th Edition(CHM Version)

    SOURCE :
        Braunwald's Heart Disease - A Textbook Of Cardiovascular Medicine - 9th Edition

    AUTHORS :
        Robert O. Bonow, MD
            Max and Lilly Goldberg Distinguished Professor of Cardiology, Vice Chairman, Department of Medicine, Director, Center for Cardiac Innovation, Northwestern University Feinberg School of Medicine, Chicago, Illinois
        Douglas L. Mann, MD
            Lewin Chair and Professor of Medicine, Cell Biology, and Physiology, Chief, Division of Cardiology, Washington University School of Medicine in St. Louis, Cardiologist-in-Chief, Barnes-Jewish Hospital, Saint Louis, Missouri
        Douglas P. Zipes, MD
            Distinguished Professor, Professor Emeritus of Medicine, Pharmacology, and Toxicology, Director Emeritus, Division of Cardiology and the Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, Indiana
        Peter Libby, MD
            Mallinckrodt Professor of Medicine, Harvard Medical School, Chief, Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts

    SUMMARY :
        Advances in cardiovascular science and practice continue at a breathtaking rate. As the knowledge base expands, it is important to adapt our learning systems to keep up with progress in our field. We are pleased to present the ninth edition of Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine as the hub of an ongoing, advanced learning system designed to provide practitioners, physicians-in-training, and students at all levels with the tools needed to keep abreast of rapidly changing scientific foundations, clinical research results, and evidence-based medical practice.
        In keeping with the tradition established by the previous editions of Braunwald's Heart Disease, the ninth edition covers the breadth of cardiovascular practice, highlighting new advances and their potential to transform the established paradigms of prevention, diagnosis, and treatment. We have thoroughly revised this edition to keep the content vibrant, stimulating, and up-to-date. Twenty-four of the 94 chapters are entirely new, including nine chapters that cover topics not addressed in earlier editions. We have added 46 new authors, all highly accomplished and recognized in their respective disciplines. All chapters carried over from the eighth edition have been thoroughly updated and extensively revised. This edition includes nearly 2500 figures, most of which are in full color, and 600 tables. We have continued to provide updated sections on current guidelines recommendations that complement each of the appropriate individual chapters.
        A full accounting of these changes in the new edition cannot be addressed in the space of this Preface, but we are pleased to present a number of the highlights. The ninth edition includes two entirely new chapters—ethics in cardiovascular medicine by Paul Mueller and design and conduct of clinical trials by Elliot Antman—that supplement the initial section on the fundamentals of cardiovascular disease. Thomas Gaziano has joined J. Michael Gaziano in authoring the first chapter on the global burden of cardiovascular disease. With recognition of the increasing relevance of genetics, J.G. Seidman joins Reed Pyeritz and Christine Seidman in the updated chapter on inherited causes of cardiovascular disease, and David Tester and Michael Ackerman have contributed a new chapter on the genetics of cardiac arrhythmias.
        Acknowledging the unremitting burden and societal impact of heart failure, the section on heart failure receives continued emphasis and has undergone extensive revision, including five new chapters. Barry Greenberg teams with Andrew Kahn in addressing the clinical approach to the patient with heart failure; Mihai Georghiade, Gerasimos Filippatos, and Michael Felker provide a fresh look at the evaluation and management of acute heart failure; Michael Acker and Mariell Jessup address advances in surgical treatment the failing heart; Mandeep Mehra and Bartley Griffith discuss the role of device therapy in assisted circulation; and William Abraham reviews the emerging role of devices for monitoring and managing heart failure.
        The chapters that address cardiovascular imaging have kept abreast of all of the exciting advances in this field. Raymond Kwong and Allen Taylor have written excellent and comprehensive new chapters on cardiac magnetic resonance and cardiac computed tomography, respectively, with accompanying sections addressing the American College of Cardiology appropriate use criteria for the use of these advanced technologies. Updated ACC appropriate use criteria also follow the chapters on echocardiography and nuclear cardiology. In addition, the imaging section has been further enhanced by the inclusion of two new chapters focusing on the evolving applications of intravascular ultrasound, authored by Jean-Claude Tardif and Philippe L’Allier, and cardiovascular molecular imaging, provided by Peter Libby, Farouc Jaffer, and Ralph Weissleder.
        In recognition of the growing importance of atrial fibrillation in cardiovascular practice, a new chapter devoted to the evaluation and treatment of this rhythm disturbance, authored by Fred Morady and Douglas Zipes, has been added to the section on cardiac arrhythmias. The other updated chapters in the heart rhythm section continue to inform our readers on the current state-of-the-art in this important aspect of heart disease.
        Dariush Mozaffarian and Edzard Ernst have added expertly authored new chapters on nutrition and complementary medicine, respectively, to the section on preventive cardiology. In the atherosclerotic disease section, Marc Sabatine joins Chris Cannon in the revised discussion of the approach to the patient with chest pain, and William Boden joins David Morrow in a new chapter on stable ischemic heart disease. Deepak Bhatt teams with Jeffrey Popma in creating a new chapter on percutaneous coronary intervention, and he joins Andrew Eisenhauer and Christopher White in updating the discussion on endovascular treatment of noncoronary vascular disease. We welcome John Webb to our authorship team with his new chapter on catheter-based interventions in structural heart disease that includes discussion of the exciting novel catheter-based techniques for repair and replacement of cardiac valves. Our other new chapters include a fresh commentary on diseases of the aorta by Alan Braverman, Robert Thompson, and Luis Sanchez; diabetes and cardiovascular disease by Darren McGuire; hemostasis, thrombosis, and fibrinolysis by Jeffrey Weitz; and psychiatric and behavioral aspects of cardiovascular disease by Viola Vaccarino and Douglas Bremner. Finally, we are delighted that Jos? Ramires, Andrei Sposito, Ed?cio Cunha-Neto, and Maria de Lourdes Higuchi have expanded our discussion of the global nature of cardiovascular disease by contributing an excellent chapter on the pathophysiology, evaluation, and treatment of Chagas’ disease.
        We are indebted to all of our authors for their considerable time, effort, and commitment to maintaining the high standards of Braunwald's Heart Disease. As excited as we are about bringing this edition of the text to fruition, we are even more energized regarding the expanding Braunwald's Heart Disease website. The electronic version of this work on the companion Expert Consult website includes greater content in terms of figures and tables than the print version can accommodate. Figures and tables can be downloaded directly from the website for electronic slide presentations. In addition, we have a growing portfolio of video and audio content that supplements the print content of many of our chapters. Dr. Braunwald personally updates the chapter content on a weekly basis, thus creating a truly unique living textbook with expanding content that includes the latest research, clinical trials, and expert opinion.
        Moreover, the family of Braunwald's Heart Disease companion texts continues to expand, providing detailed expert content for the subspecialist across the broad spectrum of cardiovascular conditions. These include: Clinical Lipidology, edited by Christie Ballantyne; Clinical Arrhythmology and Electrophysiology, authored by Ziad Issa, John Miller, and Douglas Zipes; Heart Failure, edited by Douglas Mann; Valvular Heart Disease, by Catherine Otto and Robert Bonow; Acute Coronary Syndromes, by Pierre Th?roux; Preventive Cardiology, by Roger Blumenthal, JoAnne Foody, and Nathan Wong; Cardiovascular Nursing, by Debra Moser and Barbara Riegel; Mechanical Circulatory Support, by Robert Kormos and Leslie Miller; Hypertension, by Henry Black and William Elliott; Cardiovascular Therapeutics, by Elliott Antman and Marc Sabatine; Vascular Medicine, by Marc Creager, Joshua Beckman, and Joseph Loscalzo; and recent atlases on cardiovascular imaging such as Cardiovascular Magnetic Resonance, by Christopher Kramer and Gregory Hundley; Cardiovascular Computed Tomography, by Allen Taylor; and Nuclear Cardiology, by Ami Iskandrian and Ernest Garcia.
        The ninth edition of Braunwald's Heart Disease does indeed represent the central hub of a burgeoning cardiovascular learning system that can be tailored to meet the needs of all individuals engaged in cardiovascular medicine, from the accomplished subspecialist practitioner to the beginning student of cardiology. Braunwald's Heart Disease aims to provide the necessary tools to navigate the ever-increasing flow of complex information seamlessly.

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